Cell Method (European Pharmacopoeia)
A variation of the paddle over disk method as described in the European Pharmacopoeia "Dissolution test for transdermal patches (2.9.4)". The extraction cell is placed flat on the bottom of the vessel. Distance between the paddle and the surface of the patch should be 25mm ±2mm. After introduction of the cell stirring should start immediately, suggested speed in the European Pharmacopoeia is 100rpm.
Extraction cell ø20mm/3.14cm2 cover and ø27mm/1.48ml reservoir
PSEXCELL-27
Extraction cell ø32mm/8.03cm2 cover and ø38mm/2.94m; reservoir
PSEXCELL-38
Extraction cell ø40mm/12.56cm2 cover and ø45mm/4.13ml reservoir
PSEXCELL-45