Dissolution Accessories launched a new Vertical glass Permeation Cell for ex-vivo or in-vitro determination of skin permeation and skin penetration of active pharmaceutical ingredients, in co-operation with a major Pharmaceutical Company.

Our vertical glass Permeation cell model is characterized by its permanently filled section inside the acceptor chamber ensuring that the acceptor medium permanently covers the area under the membrane or skin and air bubbles entering the system during sampling cannot reach this area.

Furthermore, there is no mechanic impact on the membrane or skin during sampling. This is additionally supported by the pressure balance, which ensures a compensation of the pressure during sampling. Through this modification, very fragile membranes like mucous tissues or heat separated epidermis can be tested with a minimal number of outliers. The cell volume is designed for 10 mL. The permeation area of the Permeation cell is circa 65mm².

Due to the horizontal alignment of the skin liquid, solid and semi-solid dosage forms can be tested.

Click here to view the different types we can offer you.